In the first of a long line of James Bond movies, Bond is sent to Jamaica to investigate the mysterious disappearance of a British Secret Service Agent. Several attempts on his life and various sinister clues lead Agent 007 to a clandestine island inhabited by the diabolical Dr. No. Bond meets up with a beautiful nature-girl and together they find their fate in the hands of the ruthless scientist, who will stop at nothing to prevent interference with his malevolent schemes.
This is the first appearance of the United States CIA Agent, Felix Leiter, played by Jack Lord in this Bond film. Agent Leiter appears in 7 of the Bond films and is protrayed by the same actor in only 2 of the films. He even changes color.